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Nanocomposite Hydrogels for Tissue Engineering Applications

Abstract

Tissue engineering is an important field of regenerative medicine which combines scaffolds and cell transplantation to develop substitute tissues and/or promote tissue regeneration. Hydrogel, a three-dimensional network with high water content and biocompatibility, has been widely used as scaffolds to mimic structure and properties of tissues. However, the low mechanical strength and limited functions of the traditional hydrogels greatly limited their applications in tissue engineering. Recently, nanocomposite hydrogel, with its advantages of high mechanical property and some unique properties (such as electrical conductivity, antibacterial, antioxidation, magnetic responsiveness, etc.), has emerged as the most versatile and innovative technology which provides a new opportunity as a unique tool for fabricating hydrogels with excellent properties. In this review, we summarize the recent advances in fabricating nanocomposite hydrogels and their applications in tissue engineering. Meanwhile, the future and prospects of nanocomposite hydrogels for tissue engineering have also been discussed.

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Article information


Submitted
15 May 2020
Accepted
25 Jun 2020
First published
26 Jun 2020

Nanoscale, 2020, Accepted Manuscript
Article type
Review Article

Nanocomposite Hydrogels for Tissue Engineering Applications

H. Zhao, M. Liu, Y. Zhang, J. Yin and R. Pei, Nanoscale, 2020, Accepted Manuscript , DOI: 10.1039/D0NR03785K

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