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Gold Nanospheres and Nanorods for Anti-Cancer Therapy: comparative studies of fabrication, surface-decoration, and anti-cancer treatments

Abstract

Various gold nanoparticles have been explored as cancer therapeutics because they can be widely engineered for efficient drug carriers, diagnostic agents, and photo-irradiated therapy. In the current review, we focused on shape-dependent biomedical applications of the gold nanoparticles including gold nanospheres and nanorods. Fabrication and functionalization strategies of two different gold nanoparticles for anti-cancer therapy were introduced and the distinguishing performance depending on the shape was discussed to suggest the best carrier shape for specific application. Moreover, recent advances in anti-cancer immunotherapy using gold nano-carriers is suggested. Thus, this comparative review can be helpful to decide suitable shapes and surface-modification strategies for preparing various gold nanoparticle-based therapeutics in anti-cancer therapy

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Article information


Submitted
28 Feb 2020
Accepted
22 Jun 2020
First published
22 Jun 2020

Nanoscale, 2020, Accepted Manuscript
Article type
Review Article

Gold Nanospheres and Nanorods for Anti-Cancer Therapy: comparative studies of fabrication, surface-decoration, and anti-cancer treatments

W. Mao, Y. Son and H. S. Yoo, Nanoscale, 2020, Accepted Manuscript , DOI: 10.1039/D0NR01690J

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