Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Multiform DNA origami arrays using minimal logic control

Author affiliations

Abstract

Self-assembled DNA nanostructures significantly contribute to DNA nanotechnology. Algorithmic guiding of the assembly of DNA arrays remains a challenge in nanoarchitecture. Usually, the more sophisticated a DNA nanoarchitecture, the more DNA connections with specific sequences are required. This study aimed to investigate the feasibility of using the minimum pairs of DNA connection strands to implement algorithm-based self-assembly with finite DNA origamis. We found that the DNA origami linking complexity was markedly reduced. By rotating and turning the origami tile in different linking directions, we obtained 2 × 2 arrays of DNA origamis using a pair of DNA connections, 2 × 4 arrays using two pairs of DNA connections, and 4 × 4 arrays using three pairs of connection strands. We further analysed the effects of distortion on array formation. Overall, this study presents a hierarchical assembly strategy with minimal connections to generate multi-scale DNA arrays.

Graphical abstract: Multiform DNA origami arrays using minimal logic control

Back to tab navigation

Supplementary files

Article information


Submitted
29 Jan 2020
Accepted
18 May 2020
First published
20 May 2020

Nanoscale, 2020, Advance Article
Article type
Paper

Multiform DNA origami arrays using minimal logic control

C. Chen, J. Xu and X. Shi, Nanoscale, 2020, Advance Article , DOI: 10.1039/D0NR00783H

Social activity

Search articles by author

Spotlight

Advertisements