Jump to main content
Jump to site search


Regulating the Pro- and Anti-Oxidant Capability of Bimetallic Nanozymes for Detection of Fe2+ and Protection of Monascus pigments

Abstract

The emerging properties of mimicking enzymes open up new horizons for nanomaterials. Regulating the enzyme-like activity and exploiting application is currently the hot topics for nanozymes. Among the activities, the pro-oxidant and antioxidant capability of nanozymes is important to determine their unique physiological functions. In this paper, we demonstrate that PtRu NPs possess multiple enzyme-like activities (e.g. peroxidase, oxidase, ferroxidase, catalase and SOD) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity. The PtRu bimetallic nanozymes therefore show pro-oxidant and anti-oxidant functions. It was found that the enzyme-like activities of PtRu NPs is highly dependent on the Pt/Ru molar ratio and has a similar trend in the order of activity: Pt90Ru10 > Pt75Ru25 > Pt > Pt40Ru60, indicating the proper alloying Pt with Ru can enhance both pro- and anti-oxidant capability. By employing the ferroxidase-like activity and catalase-like activity, we verified the application of PtRu nanozymes in the detection of Fe2+ ions, and tried for the first time to protect Monascus pigments (MPs) from hydrogen peroxide oxidation. These results not only provide an effective way to optimize the pro- and anti-oxidant capability of nanozymes, but also provide prospects for the application of nanozymes in protecting biologically active natural products.

Back to tab navigation

Article information


Submitted
29 Nov 2019
Accepted
07 Jan 2020
First published
08 Jan 2020

Nanoscale, 2020, Accepted Manuscript
Article type
Paper

Regulating the Pro- and Anti-Oxidant Capability of Bimetallic Nanozymes for Detection of Fe2+ and Protection of Monascus pigments

C. Liu, Y. Yan, X. Zhang, Y. Mao, X. Ren, C. Hu, W. He and J. Yin, Nanoscale, 2020, Accepted Manuscript , DOI: 10.1039/C9NR10135G

Social activity

Search articles by author

Spotlight

Advertisements