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Enhanced eradication of bacterial biofilms with DNase I-loaded silver-doped mesoporous silica nanoparticles

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Abstract

Deoxyribonuclease I (DNase I) was successfully loaded and delivered by silver-doped mesoporous silica nanoparticles (MSN-Ag) for biofilm treatments. This nanoformulation showed enhanced antibacterial effects for both Gram-negative and Gram-positive biofilms by promoting the biofilm biomass dispersing ability of DNase I.

Graphical abstract: Enhanced eradication of bacterial biofilms with DNase I-loaded silver-doped mesoporous silica nanoparticles

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Publication details

The article was received on 02 Oct 2019, accepted on 16 Nov 2019 and first published on 19 Nov 2019


Article type: Communication
DOI: 10.1039/C9NR08467C
Nanoscale, 2020, Advance Article

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    Enhanced eradication of bacterial biofilms with DNase I-loaded silver-doped mesoporous silica nanoparticles

    W. Tasia, C. Lei, Y. Cao, Q. Ye, Y. He and C. Xu, Nanoscale, 2020, Advance Article , DOI: 10.1039/C9NR08467C

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