Jump to main content
Jump to site search


Quantification of magnetic nanoparticles by compensating for multiple environment changes simultaneously

Author affiliations

Abstract

The quantification of magnetic nanoparticles is important for many applications, especially for in vivo biosensing. The magnetization harmonics used in spectroscopy of magnetic nanoparticles can be used to estimate nanoparticle number or weight. However, other effects such as temperature or relaxation time change can also influence the nanoparticle magnetization. Therefore, it is necessary to compensate for these factors when estimating the amount of magnetic nanoparticles. This paper shows through simulation that a two-dimensional scaling method can be used to improve the accuracy of nanoparticle quantification, especially when multiple effects are present which can influence the nanoparticle magnetization. Finally, an experiment was performed on a Magnetic Spectroscopy of Brownian motion (MSB) apparatus to demonstrate this method, and nanoparticle weight was determined with a mean error of 1.3 ng (1.81%).

Graphical abstract: Quantification of magnetic nanoparticles by compensating for multiple environment changes simultaneously

Back to tab navigation

Publication details

The article was received on 25 Sep 2019, accepted on 27 Nov 2019 and first published on 27 Nov 2019


Article type: Paper
DOI: 10.1039/C9NR08258A
Nanoscale, 2020, Advance Article

  •   Request permissions

    Quantification of magnetic nanoparticles by compensating for multiple environment changes simultaneously

    Y. Shi, D. Jyoti, S. W. Gordon-Wylie and J. B. Weaver, Nanoscale, 2020, Advance Article , DOI: 10.1039/C9NR08258A

Search articles by author

Spotlight

Advertisements