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Naturally occurring [4 + 2] type terpenoid dimers: sources, bioactivities and total syntheses

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Abstract

Covering: up to January 2020

[4 + 2] type terpenoid dimers are natural products biosynthetically derived from [4 + 2] cycloaddition between two terpenoid monomers. They have attracted the attention of scientists due to their complex architectures, biological activities, natural production pathways and synthetic challenges. In this review article, we highlight recent research progress on naturally occurring [4 + 2] type terpenoid dimers, including their sources, bioactivities, biosynthetic hypotheses and total chemical syntheses.

Graphical abstract: Naturally occurring [4 + 2] type terpenoid dimers: sources, bioactivities and total syntheses

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Article information


Submitted
19 Jun 2019
First published
08 Jun 2020

Nat. Prod. Rep., 2020, Advance Article
Article type
Review Article

Naturally occurring [4 + 2] type terpenoid dimers: sources, bioactivities and total syntheses

B. Liu, S. Fu and C. Zhou, Nat. Prod. Rep., 2020, Advance Article , DOI: 10.1039/C9NP00037B

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