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Oxidative stress and antioxidant capacity: development and prospects

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Abstract

Chemical technology-based oxidative stress evaluation methods are of particular significance in practical applications. Reactive oxygen species/reactive nitrogen species (ROS/RNS) are inevitable metabolic by-products of the metabolism of the vital processes in living organisms. It has been hypothesized that the redox reaction balance could be coordinated with drugs and other interventions to prevent or treat diseases. Several indicators have been tested as evaluation standards in this field but standardized indicators have been difficult to achieve due to the complex regulation of the redox reactions in different organisms. Therefore, it is inevitable to use multiple methods based on different principles in order to evaluate oxidative stress and antioxidant capacity. In this review, we summarized the oxidative stress and the antioxidant capacity evaluation methods used in various organisms and antioxidant-using methods. We also described the strengths and weaknesses of each method, as well as potential directions for the development of new technologies.

Graphical abstract: Oxidative stress and antioxidant capacity: development and prospects

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Article information


Submitted
23 Apr 2020
Accepted
05 Jun 2020
First published
08 Jun 2020

New J. Chem., 2020, Advance Article
Article type
Perspective

Oxidative stress and antioxidant capacity: development and prospects

X. Hu, D. Dong, M. Xia, Y. Yang, J. Wang, J. Su, L. Sun and H. Yu, New J. Chem., 2020, Advance Article , DOI: 10.1039/D0NJ02041A

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