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Novel phthalocyanine-based micelles/PNIPAM composite hydrogels: spatially/temporally controlled drug release triggered by NIR laser irradiation

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Abstract

Near-infrared (NIR) light-responsive hydrogels hold significant potential for biomedical application, especially in the remote-controlled release of anticancer drugs. Herein, we report a novel NIR light responsive composite hydrogel system that undergoes structural changes to realize drug delivery and precise release, which is constructed by a poly(N-isopropylacrylamide) network and a photothermal agent, 4OCSPC/F127 micelles.

Graphical abstract: Novel phthalocyanine-based micelles/PNIPAM composite hydrogels: spatially/temporally controlled drug release triggered by NIR laser irradiation

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Article information


Submitted
15 Apr 2020
Accepted
29 Apr 2020
First published
07 May 2020

New J. Chem., 2020, Advance Article
Article type
Letter

Novel phthalocyanine-based micelles/PNIPAM composite hydrogels: spatially/temporally controlled drug release triggered by NIR laser irradiation

L. Li, W. Zhao, Z. Qu, L. Shi, S. Tan, E. Ha, T. Jia and T. Sun, New J. Chem., 2020, Advance Article , DOI: 10.1039/D0NJ01882A

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