Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Transition metal ions induced secondary structural transformation in a hydrophobized short peptide amphiphile

Author affiliations

Abstract

The precise control over self-assembling structures created by a rationally designed hydrophobized short peptide amphiphile (sPA) was studied. Bioactive transition metal ions were used to transform the supramolecular structures of this sPA. We aimed to understand the role of different transition metal ions in modulating the self-assembly of the sPAs. The presence and contribution of various secondary structures were quantitatively studied by Fourier transform infrared (FT-IR) spectroscopy, which corresponded well with microscopy observations and was further supported by computational methods. The rational incorporation of di-phenylalanine in a previously designed sPA sequence was the new addition to the sequentially studied sPAs and represents another method of alteration that can impart data regarding ion-responsive behavior to the self-assembly process. Such an approach will contribute to the design and development of stimuli-responsive novel biomaterials for numerous applications.

Graphical abstract: Transition metal ions induced secondary structural transformation in a hydrophobized short peptide amphiphile

Back to tab navigation

Supplementary files

Article information


Submitted
27 Mar 2020
Accepted
06 May 2020
First published
07 May 2020

New J. Chem., 2020, Advance Article
Article type
Paper

Transition metal ions induced secondary structural transformation in a hydrophobized short peptide amphiphile

R. Singh, N. K. Mishra, N. Singh, P. Rawal, P. Gupta and K. B. Joshi, New J. Chem., 2020, Advance Article , DOI: 10.1039/D0NJ01501F

Social activity

Search articles by author

Spotlight

Advertisements