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Issue 20, 2020
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MOF-5 as a highly efficient and recyclable catalyst for one pot synthesis of 2,4-disubstituted quinoline derivatives

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Abstract

A MOF-5-catalyzed three-component coupling reaction was developed as an efficient approach for the synthesis of 2,4-disubstituted quinoline derivatives via a one pot three-component reaction of aromatic amines, aldehydes and alkynes with excellent yields. The easy recovery and reusability of the catalyst, broad substrate scope, short reaction time, high yields of products and solvent-free conditions make this protocol practical, environmentally friendly and economically attractive.

Graphical abstract: MOF-5 as a highly efficient and recyclable catalyst for one pot synthesis of 2,4-disubstituted quinoline derivatives

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Supplementary files

Article information


Submitted
16 Mar 2020
Accepted
29 Apr 2020
First published
30 Apr 2020

New J. Chem., 2020,44, 8614-8620
Article type
Paper

MOF-5 as a highly efficient and recyclable catalyst for one pot synthesis of 2,4-disubstituted quinoline derivatives

S. Xiao, C. Ma, J. Di and Z. Zhang, New J. Chem., 2020, 44, 8614
DOI: 10.1039/D0NJ01301C

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