Molecular recognition of methamphetamine by carboxylatopillar[5]arene: drug-dependent complexation stoichiometry and insights into medical applications

Abstract

The molecular recognition of the carboxylatopillar[5]arene on methamphetamine showed interconversion between H₂:G H:G stoichiometries with dependence on drug concentration. The study simulated conditions of severe metabolic acidosis (pH 7.00) and presented intelligent and promising dynamics for the removal of overdosed drugs or poisons in the circulatory system.