Jump to main content
Jump to site search


Synthesis, photophysics and biomolecules interactive studies of new hybrid benzo-2,1,3-thiadiazoles.

Abstract

Four new hybrid molecules containing benzo-2,1,3-thiadiazole, benzofuran and arylselanyl moieties, named 4,7-bis(3-(arylselanyl)benzofuran-2-yl)benzo[c][1,2,5]thiadiazoles were designed and synthesized in good yields through an electrophilic cyclization of 4,7-bis((2-methoxyphenyl)ethynyl)benzo[c][1,2,5]thiadiazole 1 and diaryl diselenides 2 using trichloroisocyanuric acid to generate electrophilic arylselanyl species. Photophysical properties of compounds 3a-d were investigated using UV-vis absorption and emission fluorescence analysis. The emission fluorescence analysis showed a yellow-orange region emission. Large Stokes shifts values were observed for all new derivatives and attributed to the ICT state and to the electron-substituent properties. The biomolecule-binding DNA and HSA-binding interactions were also investigated by experimental and theoretical methods.

Back to tab navigation

Supplementary files

Article information


Submitted
29 Nov 2019
Accepted
14 Jan 2020
First published
15 Jan 2020

New J. Chem., 2020, Accepted Manuscript
Article type
Paper

Synthesis, photophysics and biomolecules interactive studies of new hybrid benzo-2,1,3-thiadiazoles.

J. Neto, R. Krüger, R. Balaguez, M. G. Fronza, T. Acunha, R. da Silva Oliboni, L. Savegnago, B. A. Iglesias and D. Alves, New J. Chem., 2020, Accepted Manuscript , DOI: 10.1039/C9NJ05932F

Social activity

Search articles by author

Spotlight

Advertisements