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Mastering bioactive coatings of metal oxide nanoparticles and surfaces through phosphonate dendrons

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Abstract

We reported herein an efficient method for constructing dendritic bisphosphonic acid tweezers of generation 1 and 2, which have been proven as versatile surface coatings for metal oxides implants or nanoparticles. These dendritic structures were successfully utilized for different purposes: (i) biocompatible coverings for iron oxide nanoparticles through in vitro assays, (ii) antifouling surface coatings for silica through quartz crystal microbalance studies, and (iii) stabilizing ligands for magnetic nanoparticle–microbubble conjugates via preliminary Langmuir monolayer studies.

Graphical abstract: Mastering bioactive coatings of metal oxide nanoparticles and surfaces through phosphonate dendrons

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Article information


Submitted
06 Nov 2019
Accepted
20 Jan 2020
First published
30 Jan 2020

New J. Chem., 2020, Advance Article
Article type
Paper

Mastering bioactive coatings of metal oxide nanoparticles and surfaces through phosphonate dendrons

D. Nguyen, L. Hugoni, M. Filippi, F. Perton, D. Shi, E. Voirin, L. Power, G. Cotin, M. Krafft, A. Scherberich, P. Lavalle, S. Begin-Colin and D. Felder-Flesch, New J. Chem., 2020, Advance Article , DOI: 10.1039/C9NJ05565G

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