Green synthesis and characterization of novel Mn-MOFs with catalytic and antibacterial potentials

Abstract

This study focused on the synthesis of a new manganese-based metal–organic framework and the investigation of its application aspects. A Mn-MOF nanostructure, namely UoB-4, was prepared using a Schiff base organic linker (H₂bbda: 4,4′-[benzene-1,4-diylbis(methylylidenenitrilo)]dibenzoic acid) under ultrasound irradiation. The structure of the as-synthesized UoB-4 was characterized via PXRD, TGA, CHNO, ICP, TEM, BET, and FTIR techniques. The catalytic performance of UoB-4 was evaluated in the reactions of Hantzsch for the synthesis of 1,4-dihydropyridines and alcohol oxidation. The products of both reactions were obtained with high yields under green conditions. A recycling study of UoB-4 revealed that it can be used as a recoverable stable heterogeneous catalyst without significant loss in performance. In the next step of this study, the efficiency of UoB-4 was evaluated, showing the biological potential as an antibacterial agent. Its antibacterial activity was tested against Bacillus cereus and Escherichia coli in vitro by determining the diameter of the inhibition zone in the disc diffusion method. The results indicated the acceptable activity of UoB-4 against both Gram-positive and Gram-negative bacteria. The antibacterial activity of UoB-4 was greater towards Gram-positive bacteria (B. cereus) compared to that towards Gram-negative one (E. coli). These results open the mentality that there is the synthesis possibility of Mn-based MOFs with various application aspects and high performance.