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A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal–organic framework and miRNA

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Abstract

A new strategy of using a MOF as an effective amplifier in a QCM miRNA sensor was presented based on the selective interaction between a MOF (UiO-66) with different zeta potentials and different miRNAs. The signal can be significantly enhanced, which leads to significantly improved performance in miRNA detection.

Graphical abstract: A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal–organic framework and miRNA

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Article information


Submitted
06 Sep 2019
Accepted
19 Dec 2019
First published
20 Dec 2019

New J. Chem., 2020, Advance Article
Article type
Letter

A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal–organic framework and miRNA

D. Ma, S. Zheng, J. Fan, S. Cai, Z. Dai, X. Zou, S. Teng and W. Zhang, New J. Chem., 2020, Advance Article , DOI: 10.1039/C9NJ04600C

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