Jump to main content
Jump to site search


Sm2O3 nanorod-modified graphite paste electrode for trace level voltammetric determination of acetaminophen and ciprofloxacin

Author affiliations

Abstract

Samarium oxide (Sm2O3) nanorods were synthesized through a sol–gel method in the presence of poly(ethylene glycol) as a structure-directing subagent. The transformation of the crystalline phase, crystallinity, bonding configurations, and morphology with calcination temperature was investigated by using powder X-ray diffraction, FESEM, XPS, and TEM. Furthermore, various spectroscopic analyses were done using FTIR, UV-Vis, and photoluminescence. A composite of Sm2O3 nanorods and graphite was used to prepare an electrochemical sensor for the detection of two different drug molecules in a binary mixture, namely acetaminophen (AC) and ciprofloxacin (CP). The effects of the crystalline phase on the electrocatalytic activity were analyzed. The modified electrode showed high sensitivity (93 μA μM−1 cm−2 for AC and 6.5 μA μM−1 cm−2 for CP) towards the drug molecules during the voltammetric determination. An optimized composition (3 : 7 Sm2O3 : graphite) of the modified electrode showed the best analytical performance. The strongest differential pulse voltammetric oxidation peaks for AC and CP were at around 533 ± 3 mV and 976 ± 043 mV, respectively. Anodic oxidation peaks were well-separated for effective analysis within a mixture. The sensor response was linear within the concentration range of 0.001–0.01–300 μM and 0.05–1–170 μM for AC and CP, respectively. The detection limits were 0.1 nM for AC and 5 nM for CP (S/N 3). The Sm2O3-9-3/GP electrode showed excellent analytical performance when analyzing spiked urine and pharmaceutical samples.

Graphical abstract: Sm2O3 nanorod-modified graphite paste electrode for trace level voltammetric determination of acetaminophen and ciprofloxacin

Back to tab navigation

Supplementary files

Article information


Submitted
29 Aug 2019
Accepted
13 Dec 2019
First published
16 Dec 2019

New J. Chem., 2020, Advance Article
Article type
Paper

Sm2O3 nanorod-modified graphite paste electrode for trace level voltammetric determination of acetaminophen and ciprofloxacin

S. Biswas, H. Naskar, S. Pradhan, Y. Chen, Y. Wang, R. Bandyopadhyay and P. Pramanik, New J. Chem., 2020, Advance Article , DOI: 10.1039/C9NJ04446A

Social activity

Search articles by author

Spotlight

Advertisements