Nanomaterials for Regulation of Tumor Microenvironment and Theranostics
Cancer has become one of the primary threatens of human beings and traditional therapies (including surgery, chemotherapy and radiotherapy) show the restricted therapeutic effect as the complexity of tumor biology. How to utilize the differences between tumor microenvironment (TME) and healthy tissues as well as explore new nanoplatforms that can realize early diagnosis, effective and non-toxic therapy are challenges in cancer theranostics. Numerous researchers have designed multifunctional nanomaterials and investigated their personalized therapy and regulation abilities toward the TME including the oxygen generation, glutathione consumption as well as the production of reactive oxygen species and multi-model imaging effects. This review will introduce the latest progress in the design of multi-functional nanomedicines for the regulation of TME and their theranostics, and it will provide a critical angle for the future development of nanomedicine.
- This article is part of the themed collection: Recent Review Articles