Jump to main content
Jump to site search

Issue 2, 2020
Previous Article Next Article

Sesamol: a powerful functional food ingredient from sesame oil for cardioprotection

Author affiliations

Abstract

Phytophenols are important bioactive food based chemical entities, largely present in several natural sources. Among them, sesamol is one of the key natural phenols found in sesame seeds, Piper cubeba etc. Several studies have reported that sesame oil is a potent cardioprotective functional food. Papers on the utility of sesamol in sesame oil (the chemical name of sesamol is methylenedioxyphenol, MDP) have appeared in the literature, though there is no single concise review on the usefulness of sesamol in sesame oil in CVD in the literature. Cardiovascular disease (CVD) is the most challenging health problem encountered by the global population. There has been increasing interest in the growth of effective cardiovascular therapeutics, specifically of natural origin. Among various natural sources of chemicals, phytochemicals are micronutrients and bio-compatible scaffolds having an extraordinary efficacy at multiple disease targets with minimal or no adverse effect. This review offers a perspective on the existing literature on functional ingredients in sesame oil with particular focus on sesamol and its derivatives having nutritional and cardioprotective properties. This is demonstrated to have shown a specifically modulating oxidative enzyme myeloperoxidase (MPO) and other proteins which are detrimental to human well-being. The molecular mechanism of cardioprotection by this food ingredient is primarily attributed to the methylenedioxy group present in the sesamol component.

Graphical abstract: Sesamol: a powerful functional food ingredient from sesame oil for cardioprotection

Back to tab navigation

Article information


Submitted
16 Aug 2019
Accepted
03 Jan 2020
First published
06 Jan 2020

Food Funct., 2020,11, 1198-1210
Article type
Review Article

Sesamol: a powerful functional food ingredient from sesame oil for cardioprotection

P. Jayaraj, C. A. Narasimhulu, S. Rajagopalan, S. Parthasarathy and R. Desikan, Food Funct., 2020, 11, 1198
DOI: 10.1039/C9FO01873E

Social activity

Search articles by author

Spotlight

Advertisements