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White graphene quantum dots as electrochemical sensing platform for ferritin

Abstract

The use of hexagonal boron nitride quantum dots (hBN QDs) as an electrochemical sensor for ferritin is reported for the first time in this manuscript. These QDs were synthesized using simple method of liquid exfoliation. The synthesized material was characterized using analytical techniques such as UV-Visible, Fourier Transform Infrared (FTIR) and Raman spectroscopy, X-Ray Diffraction (XRD), and High-Resolution Transmission Electron Microscopy (HR-TEM) wherein the different aspects of the QDs were studied. These QDs were explored for their plausible application as a platform for the electrochemical detection of ferritin. For this, the electrochemical impedance spectroscopy is used as sensing technique and disposable hBN QDs functionalized screen printed electrodes were used as sensing platform. The developed immunosensor had a dynamic linear range from 10-2000 ng.mL-1 of ferritin concentration with a limit of detection of 1.306 ng.mL-1. The immunosensor was highly selective, not deviated in the presence of interfering agents and also highly reproducible.

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Article information


Submitted
25 Oct 2019
Accepted
17 Jan 2020
First published
17 Jan 2020

Faraday Discuss., 2020, Accepted Manuscript
Article type
Paper

White graphene quantum dots as electrochemical sensing platform for ferritin

S. Singh, M. Garg, R. Rani and A. Sharma, Faraday Discuss., 2020, Accepted Manuscript , DOI: 10.1039/C9FD00111E

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