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A tri-metallic palladium complex with breast cancer stem cell potency

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Abstract

A multi-nuclear, triangular-shaped palladium(II) complex is shown to equipotently kill bulk cancer cells and cancer stem cells (CSCs) in the micromolar range. The palladium(II) complex evokes CSC apoptosis by entering CSC nuclei and damaging genomic DNA.

Graphical abstract: A tri-metallic palladium complex with breast cancer stem cell potency

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Article information


Submitted
01 Jan 2020
Accepted
07 Mar 2020
First published
09 Mar 2020

Dalton Trans., 2020, Advance Article
Article type
Communication

A tri-metallic palladium complex with breast cancer stem cell potency

A. Eskandari, A. Kundu, A. Johnson, S. Karmakar, S. Ghosh and K. Suntharalingam, Dalton Trans., 2020, Advance Article , DOI: 10.1039/D0DT00006J

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