Jump to main content
Jump to site search


Lanthanide-conjugates as versatile instruments for therapy and diagnostics

Abstract

Lanthanides have demonstrated their outstanding properties in many fields of research including biology and medicinal chemistry. Unique luminescence and magnetic properties renders them the metals of choice for next generation theranostics that efficiently combine the two central pillars of medicine - diagnostics and therapy. Attached to targeting units, lanthanide complexes pave the way for real-time imaging of uptake and distribution as well as specific regulation of subcellular processes poor in side effects. This enables individualized treatment options of severe diseases characterized by alternated cell expression. The highly diverse efforts achieved as well as insights into the challenges that research has to face in upcoming years will be summarized in the present review.

Back to tab navigation

Article information


Submitted
22 Dec 2019
Accepted
10 Jan 2020
First published
14 Jan 2020

This article is Open Access

Dalton Trans., 2020, Accepted Manuscript
Article type
Frontier

Lanthanide-conjugates as versatile instruments for therapy and diagnostics

C. Herlan and S. Bräse, Dalton Trans., 2020, Accepted Manuscript , DOI: 10.1039/C9DT04851K

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

Reproduced material should be attributed as follows:

  • For reproduction of material from NJC:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
  • For reproduction of material from PCCP:
    [Original citation] - Published by the PCCP Owner Societies.
  • For reproduction of material from PPS:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
  • For reproduction of material from all other RSC journals:
    [Original citation] - Published by The Royal Society of Chemistry.

Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.


Social activity

Search articles by author

Spotlight

Advertisements