Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Lipids: chemical tools for their synthesis, modification, and analysis

Author affiliations

Abstract

Lipids remain one of the most enigmatic classes of biological molecules. Whereas lipids are well known to form basic units of membrane structure and energy storage, deciphering the exact roles and biological interactions of distinct lipid species has proven elusive. How these building blocks are synthesized, trafficked, and stored are also questions that require closer inspection. This tutorial review covers recent advances on the preparation, derivatization, and analysis of lipids. In particular, we describe several chemical approaches that form part of a powerful toolbox for controlling and characterizing lipid structure. We believe these tools will be helpful in numerous applications, including the study of lipid–protein interactions and the development of novel drug delivery systems.

Graphical abstract: Lipids: chemical tools for their synthesis, modification, and analysis

Back to tab navigation

Article information


Submitted
22 Feb 2020
First published
17 Jun 2020

Chem. Soc. Rev., 2020, Advance Article
Article type
Tutorial Review

Lipids: chemical tools for their synthesis, modification, and analysis

J. Flores, B. M. White, R. J. Brea, J. M. Baskin and N. K. Devaraj, Chem. Soc. Rev., 2020, Advance Article , DOI: 10.1039/D0CS00154F

Social activity

Search articles by author

Spotlight

Advertisements