Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.

Biohybrid robotics with living cell actuation

Author affiliations


As simulators of organisms in Nature, soft robots have been developed over the past few decades. In particular, biohybrid robots constructed by integrating living cells with soft materials demonstrate the unique advantage of simulating the construction and functions of human tissues or organs, thus attracting extensive attention and research interest. Here, we present up-to-date studies concerning biohybrid robots with various biological actuators such as contractile cells and microorganisms. After presenting the basic components including biological components and synthetic materials, the controlling methods and locomotion modalities of biohybrid robots are clarified and summarized. We then focus on the applications, especially the biomedical applications, of the biohybrid robots including drug delivery, bioimaging, and tissue engineering. The challenges and prospects for the future development of biohybrid robots are also presented.

Graphical abstract: Biohybrid robotics with living cell actuation

Back to tab navigation

Article information

29 Feb 2020
First published
17 May 2020

Chem. Soc. Rev., 2020, Advance Article
Article type
Review Article

Biohybrid robotics with living cell actuation

L. Sun, Y. Yu, Z. Chen, F. Bian, F. Ye, L. Sun and Y. Zhao, Chem. Soc. Rev., 2020, Advance Article , DOI: 10.1039/D0CS00120A

Social activity

Search articles by author