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Issue 25, 2020
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Crystal engineering of nutraceutical phytosterols: new cocrystal solid solutions

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Abstract

A cocrystal screening conducted with solid solutions of three phytosterols (β-sitosterol, campesterol and stigmasterol) and a set of coformers with strong hydrogen bond donors reveals that multicomponent solid solutions are preferentially formed instead of pure cocrystals and are much enriched with β-sitosterol with respect to stigmasterol, a natural product with cytotoxicity concerns.

Graphical abstract: Crystal engineering of nutraceutical phytosterols: new cocrystal solid solutions

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Supplementary files

Article information


Submitted
11 May 2020
Accepted
02 Jun 2020
First published
03 Jun 2020

CrystEngComm, 2020,22, 4210-4214
Article type
Communication

Crystal engineering of nutraceutical phytosterols: new cocrystal solid solutions

R. Barbas, L. Bofill, D. de Sande, M. Font-Bardia and R. Prohens, CrystEngComm, 2020, 22, 4210
DOI: 10.1039/D0CE00704H

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