Issue 88, 2020

Copper and palladium co-catalyzed highly regio-selective 1,2-hydroarylation of terminal 1,3-dienes

Abstract

A practical copper and palladium co-catalyzed highly regio-selective hydroarylation of terminal 1,3-dienes has been developed. This chemistry afforded the terminal alkenyl group containing products, which are a kind of versatile precursor for organic synthesis, from 1,3-dienes by a practical one-step reaction. With good functional group tolerance, this protocol could be used to make a series of bio-active compounds using readily accessible starting materials. The mechanism of this reaction was explored by control experiments and kinetics studies.

Graphical abstract: Copper and palladium co-catalyzed highly regio-selective 1,2-hydroarylation of terminal 1,3-dienes

Supplementary files

Article information

Article type
Communication
Submitted
06 Sep 2020
Accepted
02 Oct 2020
First published
05 Oct 2020

Chem. Commun., 2020,56, 13551-13554

Copper and palladium co-catalyzed highly regio-selective 1,2-hydroarylation of terminal 1,3-dienes

R. Zhang, Q. Li, M. Zhang, S. Chai, Y. Duan, J. Su, Q. Zhao and C. Zhang, Chem. Commun., 2020, 56, 13551 DOI: 10.1039/D0CC06007K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements