Jump to main content
Jump to site search


Rhodium-catalyzed coupling of arenes and fluorinated α-diazo diketones: synthesis of chromones

Author affiliations

Abstract

Rhodium(III)-catalyzed C–C coupling of heteroarenes and fluorinated α-diazo diketones has been realized for the facile synthesis of 3-arylchromones. The reaction proceeds via chelation-assisted C–H activation, carbene insertion, and uncatalyzed intramolecular nucleophilic aromatic substitution, with C–F cleavage being accommodated in the nucleophilic aromatic substitution step. Three classes of heteroarenes have been defined with decent functional group tolerance.

Graphical abstract: Rhodium-catalyzed coupling of arenes and fluorinated α-diazo diketones: synthesis of chromones

Back to tab navigation

Supplementary files

Article information


Submitted
20 Aug 2020
Accepted
21 Sep 2020
First published
22 Sep 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Rhodium-catalyzed coupling of arenes and fluorinated α-diazo diketones: synthesis of chromones

J. Yao, L. Kong and X. Li, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC05664B

Social activity

Search articles by author

Spotlight

Advertisements