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Issue 84, 2020
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Inflammation-responsive nanocapsules for the dual-release of antibacterial drugs

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Abstract

Herein, we design inflammation-responsive nanocapsules containing two antibiotics. The releases are programmed to be triggered under conditions occurring at the different stages of wound healing. The nanocapsules exhibit excellent antibacterial activities against Gram-positive, Gram-negative, and antibiotic-resistant bacteria. Incorporation of small amounts of nanocapsules in hydrogels leads to efficient antibacterial wound dressings.

Graphical abstract: Inflammation-responsive nanocapsules for the dual-release of antibacterial drugs

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Article information


Submitted
03 Aug 2020
Accepted
22 Sep 2020
First published
22 Sep 2020

Chem. Commun., 2020,56, 12725-12728
Article type
Communication

Inflammation-responsive nanocapsules for the dual-release of antibacterial drugs

A. Jobdeedamrong, M. Theerasilp, N. Wongsuwan, N. Nasongkla and D. Crespy, Chem. Commun., 2020, 56, 12725
DOI: 10.1039/D0CC05287F

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