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Rhamnose modified bovine serum albumin as a carrier protein promotes the immune response against sTn antigen

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Abstract

Rhamnose and sTn antigen were co-conjugated to bovine serum albumin (BSA), a weakly immunogenic carrier protein, for cancer vaccine development. The immune responses against sTn have been significantly augmented with the involvement of Rha-specific antibodies to enhance antigen uptake.

Graphical abstract: Rhamnose modified bovine serum albumin as a carrier protein promotes the immune response against sTn antigen

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Article information


Submitted
02 Aug 2020
Accepted
12 Oct 2020
First published
12 Oct 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Rhamnose modified bovine serum albumin as a carrier protein promotes the immune response against sTn antigen

H. Lin, H. Hong, J. Wang, C. Li, Z. Zhou and Z. Wu, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC05263A

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