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Issue 77, 2020
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Autocatalytic DNAzyme assembly for amplified intracellular imaging

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Abstract

The autocatalytic HCR-DNAzyme platform was constructed as a versatile amplification platform for intracellular microRNA imaging by integrating hybridization chain reaction (HCR) circuit with DNAzyme biocatalysis. The HCR-assembled multifunctional DNAzyme nanowires produce new HCR triggers and numerous transducer DNAzyme amplifier, and thus shows great promise in earlier cancer diagnosis.

Graphical abstract: Autocatalytic DNAzyme assembly for amplified intracellular imaging

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Article information


Submitted
01 Aug 2020
Accepted
02 Sep 2020
First published
02 Sep 2020

Chem. Commun., 2020,56, 11410-11413
Article type
Communication

Autocatalytic DNAzyme assembly for amplified intracellular imaging

K. Gong, Q. Wu, H. Wang, S. He, J. Shang and F. Wang, Chem. Commun., 2020, 56, 11410
DOI: 10.1039/D0CC05257D

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