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Issue 68, 2020
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Polyoxometalate-functionalized macroporous microspheres for selective separation/enrichment of glycoproteins

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Abstract

Glycoproteins always participate in various biological processes. Selective separation and enrichment of glycoproteins are of great significance for the research of pathogenesis. Herein, macroporous polymer microspheres were fabricated, and further functionalized by polyoxometalate. Thus, a simple, efficient and highly selective approach was constructed for glycoprotein enrichment from a complex matrix. The as-prepared material shows promise as a potential adsorbent in bio-separation and downstream clinical applications.

Graphical abstract: Polyoxometalate-functionalized macroporous microspheres for selective separation/enrichment of glycoproteins

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Article information


Submitted
18 Jun 2020
Accepted
20 Jul 2020
First published
20 Jul 2020

Chem. Commun., 2020,56, 9870-9873
Article type
Communication

Polyoxometalate-functionalized macroporous microspheres for selective separation/enrichment of glycoproteins

M. Wang, S. Chen, Y. Yu and J. Wang, Chem. Commun., 2020, 56, 9870
DOI: 10.1039/D0CC04244G

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