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Synthesis of Iron Oxide Nanocubes Patched Janus Magnetic Nanocarriers for Cancer Therapeutic Applications

Abstract

Janus magnetic particles, which can be customizable for various multifunctionalities, have a promising potential for cancer therapeutic carriers. Herein we synthesized iron oxide nanocubes (IONCs) patched Janus magnetic nanocarriers (IONCs-P-JMNC) using emulsification and interface evaporation/assembly. Novel IONCs patches were generated with an optimal ratio of CTAB and oleic acid coated IONCs in the emulsion. 2D assembled IONCs patched Janus magnetic porous silica nanocarriers (IONCs-P-JMNC) formed with the addition of tetraethyl orthosilicate (TEOS). The anisotropically IONCs patched Janus nanocarriers, allowing effective MRI T2* contrast and magneto-mechanical property, are expected to be used for a new type of multifunctional carriers in cancer therapeutic applications.

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Supplementary files

Article information


Submitted
21 May 2020
Accepted
29 Jun 2020
First published
29 Jun 2020

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

Synthesis of Iron Oxide Nanocubes Patched Janus Magnetic Nanocarriers for Cancer Therapeutic Applications

W. Zhang, H. Choi, B. Yu and D. Kim, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/D0CC03614E

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