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Issue 81, 2020
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Therapeutic iminoboronate-based polymersomes with a Cu(ii)-mediated Fenton reaction-enhanced ROS-response

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Abstract

Reactive oxygen species (ROS)-responsive prodrug nanoplatforms may not work efficiently due to insufficient ROS concentrations, so therapeutic polymersomes of a metallisable triamine-centered iminoboronate-functionalized amphiphilic starlike prodrug (N3-(OEG-IBCAPE)4) are prepared to show a Cu(II)-mediated Fenton reaction-enhanced ROS response.

Graphical abstract: Therapeutic iminoboronate-based polymersomes with a Cu(ii)-mediated Fenton reaction-enhanced ROS-response

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Article information


Submitted
21 May 2020
Accepted
02 Sep 2020
First published
02 Sep 2020

Chem. Commun., 2020,56, 12246-12249
Article type
Communication

Therapeutic iminoboronate-based polymersomes with a Cu(II)-mediated Fenton reaction-enhanced ROS-response

R. Cheng, G. Li, L. Fan, J. Jiang and Y. Zhao, Chem. Commun., 2020, 56, 12246
DOI: 10.1039/D0CC03607B

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