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An MRI-visible immunoadjuvant based on hollow Gd2O3 nanospheres for cancer immunotherapy

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Abstract

Hollow Gd2O3 nanospheres significantly promote the cellular uptake of a tumor antigen by antigen presenting cells, exhibit pH-dependent alteration of the MR signal intensity and markedly enhance the antitumor immunity. Hollow Gd2O3 nanospheres are promising as magnetic resonance imaging (MRI)-visible cancer immunoadjuvants for cancer immunotherapy.

Graphical abstract: An MRI-visible immunoadjuvant based on hollow Gd2O3 nanospheres for cancer immunotherapy

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Supplementary files

Article information


Submitted
19 May 2020
Accepted
22 Jun 2020
First published
22 Jun 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

An MRI-visible immunoadjuvant based on hollow Gd2O3 nanospheres for cancer immunotherapy

X. Li, X. Wang and A. Ito, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC03568H

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