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Issue 59, 2020
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Transmembrane transport of copper(i) by imidazole-functionalised calix[4]arenes

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Abstract

Here we present the first synthetic transmembrane transporters for Cu+. Calix[4]arenes with two imidazole groups have a linear coordination motif, which allows selective extraction of Cu+ into chloroform. Transmembrane transport of Cu+ into liposomes was investigated with a newly developed assay and the results open the way to biomedical applications of these Cu+ ionophores.

Graphical abstract: Transmembrane transport of copper(i) by imidazole-functionalised calix[4]arenes

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Supplementary files

Article information


Submitted
18 May 2020
Accepted
09 Jun 2020
First published
10 Jun 2020

Chem. Commun., 2020,56, 8206-8209
Article type
Communication

Transmembrane transport of copper(I) by imidazole-functionalised calix[4]arenes

N. Renier, O. Reinaud, I. Jabin and H. Valkenier, Chem. Commun., 2020, 56, 8206
DOI: 10.1039/D0CC03555F

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