Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Mitochondria-localized in situ generation of rhodamine photocage with fluorescence turn-on enabling cancer cell-specific drug delivery triggered by green light

Author affiliations

Abstract

In this work, we have developed a rhodamine dye based water-soluble, mitochondria-indicating photocage, which gets activated in the mitochondria producing a fluorescent signal and on-demand releases the caged anticancer drug, chlorambucil, in the cancer cells selectively upon irradiation of green light.

Graphical abstract: Mitochondria-localized in situ generation of rhodamine photocage with fluorescence turn-on enabling cancer cell-specific drug delivery triggered by green light

Back to tab navigation

Supplementary files

Article information


Submitted
17 May 2020
Accepted
18 Jun 2020
First published
18 Jun 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Mitochondria-localized in situ generation of rhodamine photocage with fluorescence turn-on enabling cancer cell-specific drug delivery triggered by green light

A. Paul, R. Mengji, M. Bera, M. Ojha, A. Jana and N. D. P. Singh, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC03524F

Social activity

Search articles by author

Spotlight

Advertisements