Issue 64, 2020
From the journal:

Chemical Communications

Mutual correlation evaluation of Cys and Hcy in serum through reaction activity regulated fluorescence quantification†

Yongkang Yue, ORCID logo a   Fangjun Huo, ORCID logo b   Yuting Wang,a   Kaiqing Ma, ORCID logo a   Xiaoqing Lic  and  Caixia Yin ORCID logo *a  

* Corresponding authors

a Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China
E-mail: yincx@sxu.edu.cn

b Research Institute of Applied Chemistry, Shanxi University, Taiyuan 030006, China

c Second Hospital of Shanxi Medical University, Taiyuan 030001, China

Abstract

We report herein a strategy involving using a single fluorescent probe with the assistance of two pH conditions to simultaneously detect cysteine and homocysteine quantitatively. The concentrations of Cys and Hcy in human serum samples were found to display a positive correlation, which might promote a further understanding of thiol-related diseases.

Graphical abstract: Mutual correlation evaluation of Cys and Hcy in serum through reaction activity regulated fluorescence quantification

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Article information

DOI
https://doi.org/10.1039/D0CC03457F
Article type
Communication
Submitted
14 May 2020
Accepted
26 Jun 2020
First published
29 Jun 2020

Chem. Commun., 2020,56, 9146-9149

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Mutual correlation evaluation of Cys and Hcy in serum through reaction activity regulated fluorescence quantification

Y. Yue, F. Huo, Y. Wang, K. Ma, X. Li and C. Yin, Chem. Commun., 2020, 56, 9146 DOI: 10.1039/D0CC03457F

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