Issue 57, 2020
From the journal:

Chemical Communications

LMCT transition-based red-light photochemotherapy using a tumour-selective ferrocenyl iron(iii) coumarin conjugate†

Tukki Sarkar,a   Arnab Bhattacharyya, ORCID logo *b   Samya Banerjee ORCID logo *c  and  Akhtar Hussain ORCID logo *a  

* Corresponding authors

a Depatment of Chemistry, Handique Girl's College, Guwahati, Assam, India
E-mail: akhtariisc@gmail.com

b Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, Karnataka, India
E-mail: arnab.bhattacharyya1@gmail.com

c Institute of Inorganic Chemistry, Georg-August-Universität Göttingen, Tammannstr. 4, 37077 Göttingen, Germany
E-mail: sbanerj1@uni-goettingen.de

Abstract

A rationally designed iron(III) complex (2a) with pendant ferrocene and naturally occurring coumarin (esculetin) shows LMCT transition-based mitochondria-targeted red-light (600–720 nm) induced apoptotic toxicity against cancer cells but remains innocuous in the dark and to normal cells.

Graphical abstract: LMCT transition-based red-light photochemotherapy using a tumour-selective ferrocenyl iron(iii) coumarin conjugate

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Article information

DOI
https://doi.org/10.1039/D0CC03240A
Article type
Communication
Submitted
05 May 2020
Accepted
29 May 2020
First published
15 Jun 2020

Chem. Commun., 2020,56, 7981-7984

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LMCT transition-based red-light photochemotherapy using a tumour-selective ferrocenyl iron(III) coumarin conjugate

T. Sarkar, A. Bhattacharyya, S. Banerjee and A. Hussain, Chem. Commun., 2020, 56, 7981 DOI: 10.1039/D0CC03240A

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