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LMCT transition-based red-light photochemotherapy using a tumour-selective ferrocenyl iron(iii) coumarin conjugate

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Abstract

A rationally designed iron(III) complex (2a) with pendant ferrocene and naturally occurring coumarin (esculetin) shows LMCT transition-based mitochondria-targeted red-light (600–720 nm) induced apoptotic toxicity against cancer cells but remains innocuous in the dark and to normal cells.

Graphical abstract: LMCT transition-based red-light photochemotherapy using a tumour-selective ferrocenyl iron(iii) coumarin conjugate

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Article information


Submitted
05 May 2020
Accepted
29 May 2020
First published
15 Jun 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

LMCT transition-based red-light photochemotherapy using a tumour-selective ferrocenyl iron(III) coumarin conjugate

T. Sarkar, A. Bhattacharyya, S. Banerjee and A. Hussain, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC03240A

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