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A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells

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Abstract

A rotor-based probe MRMP-1 was designed and synthesized. MRMP-1 can bind to plasma membranes very quickly and stably with remarkable fluorescence enhancement. It can be used to monitor the dynamic changes in cell membranes in real-time under stimuli conditions. Importantly, MRMP-1 is the first rotor-based fluorescent sensor to label exosomes in living cells.

Graphical abstract: A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells

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Supplementary files

Article information


Submitted
28 Apr 2020
Accepted
17 Jun 2020
First published
17 Jun 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells

L. Feng, Y. Xie, S. K. Au-Yeung, H. B. Hailu, Z. Liu, Q. Chen, J. Zhang, Q. Pang, X. Yao, M. Yang, L. Zhang and H. Sun, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC03069D

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