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Supramolecular subphthalocyanine complexes–cellular uptake and phototoxicity

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Abstract

In this communication we report on the synthesis and application of axially functionalized boron-subphthalocyanines (SubPC) which are able to form host–guest complexes with cyclodextrins. Here, a tert-butylphenyl substituted SubPC was investigated concerning its complexation with β-cyclodextrin (β-CD) and a β-cyclodextrin polymer. NMR-titrations showed the formation of a 1 : 1 complex with β-CD. These assemblies were analyzed for their cellular distribution as well as their phototoxicity towards HeLa cells.

Graphical abstract: Supramolecular subphthalocyanine complexes–cellular uptake and phototoxicity

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Supplementary files

Article information


Submitted
28 Apr 2020
Accepted
30 May 2020
First published
10 Jun 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Supramolecular subphthalocyanine complexes–cellular uptake and phototoxicity

J. Dubbert, A. Höing, N. Riek, S. K. Knauer and J. Voskuhl, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC03065A

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