Product-boosted fluorescence signal: a new approach for designing small-molecule probes for detection of peroxynitrite

Abstract

In situ self-assembled boronate ester comprising commercially available 2-formylphenylboronic acid and 2-(2′,3′-bihydroxyphenyl)benzothiazole (BHBT) is explored for the detection of ONOO⁻ with product-boosted fluorescence. The self-assembly can detect ONOO⁻ in the endoplasmic reticulum of living cells.