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N,O-Benzamide Difluoroboron Complexes as Near-infrared Probes for the Detection of β-amyloid and Tau Fibrils

Abstract

In this study, a series of organo difluoroboron probes with the BF2 benzamide moiety were designed, prepared and evaluated. Among them, 2c displayed the best optical and biological properties, and may apply as a useful near-infrared fluorescent probe for the detection of Aβ plaques and neurofibrillary tangles in AD.

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Supplementary files

Article information


Submitted
18 Apr 2020
Accepted
21 May 2020
First published
21 May 2020

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

N,O-Benzamide Difluoroboron Complexes as Near-infrared Probes for the Detection of β-amyloid and Tau Fibrils

Y. Chen, C. Yuan, T. Xie, Y. Li, B. Dai, K. Zhou, Y. Liang, J. Dai, H. Tan and M. Cui, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/D0CC02820G

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