Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds

Author affiliations

Abstract

Herein, we describe the development of a simple, high yielding and stereocontrolled strategy for the synthesis of a series of triazolopiperazines and other biologically relevant fused scaffolds from optically active amino acids. This route was applied to the synthesis of 22 scaffolds containing new, previously inaccessible vectors and used to access a novel analogue of ganaplacide.

Graphical abstract: An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds

Back to tab navigation

Supplementary files

Article information


Submitted
15 Apr 2020
Accepted
07 May 2020
First published
11 May 2020

This article is Open Access

Chem. Commun., 2020, Advance Article
Article type
Communication

An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds

H. L. Stewart, A. R. Hanby, T. A. King, A. D. Bond, T. A. Moss, H. F. Sore and D. R. Spring, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC02728F

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

Reproduced material should be attributed as follows:

  • For reproduction of material from NJC:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
  • For reproduction of material from PCCP:
    [Original citation] - Published by the PCCP Owner Societies.
  • For reproduction of material from PPS:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
  • For reproduction of material from all other RSC journals:
    [Original citation] - Published by The Royal Society of Chemistry.

Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.


Social activity

Search articles by author

Spotlight

Advertisements