Mitochondriotropic lanthanide nanorods: implications for multimodal imaging

Harwinder Singh; Sreejesh Sreedharan; Esteban Oyarzabal; Tufan Singha Mahapatra; Nicola Green; Yen-Yu Ian Shih; Manasmita Das; Jim. A. Thomas; Sumit Kumar Pramanik; Amitava Das

doi:10.1039/D0CC02698K

Mitochondriotropic lanthanide nanorods: implications for multimodal imaging†

Harwinder Singh,^ab Sreejesh Sreedharan,

^c Esteban Oyarzabal,^d Tufan Singha Mahapatra,

^ae Nicola Green,

^f Yen-Yu Ian Shih,^d Manasmita Das,*^d Jim. A. Thomas,

*^g Sumit Kumar Pramanik

*^a and Amitava Das

*^abh

Author affiliations

* Corresponding authors

^a Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat, India
E-mail: sumitpramanik@csmcri.res.in

^b Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

^c Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK

^d Center for Animal MRI (CAMRI), University of North Carolina, Chapel Hill NC 27599, USA
E-mail: dmanasmi@email.unc.edu

^e Department of Chemistry, ICFAI University Tripura, Agartala-799210, India

^f Department of Biomedical Science, University of Sheffield, Sheffield, UK

^g Department of Chemistry, University of Sheffield, Sheffield, UK
E-mail: james.thomas@sheffield.ac.uk

^h Indian Institute of Science Education and Research Kolkata, Mohanpur 741246, West Bengal, India
E-mail: amitava@iiserkol.ac.in

Abstract

Two-photon active mitochondriotropic lanthanide nanorods for high resolution fluorescence imaging. The presence of Gd in the nanorods also enabled us to utilize this material as a T₁–T₂ dual-mode contrast reagent for recording magnetic resonance images of the mouse brain.

Chemical Communications

Mitochondriotropic lanthanide nanorods: implications for multimodal imaging†

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