Issue 52, 2020

Enveloped artificial viral capsids self-assembled from anionic β-annulus peptide and cationic lipid bilayer

Abstract

Anionic artificial viral capsids were self-assembled from β-annulus-EE peptide, then complexed with lipid-bilayer-containing cationic lipids via electrostatic interaction to form enveloped artificial viral capsids. The critical aggregation concentration of the enveloped artificial viral capsid was significantly lower than that of the uncomplexed artificial viral capsid, indicating that the lipid bilayer stabilised the capsid structure.

Graphical abstract: Enveloped artificial viral capsids self-assembled from anionic β-annulus peptide and cationic lipid bilayer

Supplementary files

Article information

Article type
Communication
Submitted
11 Apr 2020
Accepted
28 May 2020
First published
28 May 2020

Chem. Commun., 2020,56, 7092-7095

Enveloped artificial viral capsids self-assembled from anionic β-annulus peptide and cationic lipid bilayer

H. Furukawa, H. Inaba, F. Inoue, Y. Sasaki, K. Akiyoshi and K. Matsuura, Chem. Commun., 2020, 56, 7092 DOI: 10.1039/D0CC02622K

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