Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Photo-driven haloazidation cyclization of 1,5-enynes having cyano groups with TMSN3 and NIS/NCS/NBS under metal-free conditions

Author affiliations

Abstract

A visible-light-driven three-component haloazidation cyclization of 1,5-enynes having cyano groups with TMSN3, and N-iodo(bromo, chloro)succinimide under metal-free and oxidant-free conditions was developed. The reaction underwent a radical addition/5-exo-dig cyclization/radical coupling process with the successive formation of C–N, C–C, and C–halogen (Cl, Br, and I) bonds, which was initiated by the addition of an azidyl radical to the carbon–carbon double bond of the 1,5-enyne.

Graphical abstract: Photo-driven haloazidation cyclization of 1,5-enynes having cyano groups with TMSN3 and NIS/NCS/NBS under metal-free conditions

Back to tab navigation

Supplementary files

Article information


Submitted
06 Apr 2020
Accepted
04 Jun 2020
First published
05 Jun 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Photo-driven haloazidation cyclization of 1,5-enynes having cyano groups with TMSN3 and NIS/NCS/NBS under metal-free conditions

L. Zou, L. Wang, L. Sun, X. Xie and P. Li, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC02471F

Social activity

Search articles by author

Spotlight

Advertisements