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Ru(ii) photosensitizers competent for hypoxic cancers via green light activation

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Abstract

A family of five heteroleptic complexes [Ru(C^N)(N^N)2][PF6] (HC^N = methyl 1-butyl-2-arylbenzimidazolecarboxylate; N^N = polypyridine) has been synthesized to act as biologically-compatible green light photosensitizers (PSs) with phototherapeutic indexes (PIs) up to higher than 700 under hypoxia (2% O2) in HeLa cancer cells under short time of irradiation.

Graphical abstract: Ru(ii) photosensitizers competent for hypoxic cancers via green light activation

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Supplementary files

Article information


Submitted
03 Apr 2020
Accepted
17 Jul 2020
First published
17 Jul 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Ru(II) photosensitizers competent for hypoxic cancers via green light activation

F. J. Ballester, E. Ortega, D. Bautista, M. D. Santana and J. Ruiz, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC02417A

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