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Issue 56, 2020
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Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm

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Abstract

A series of near-infrared and photostable Si-oxazine fluorescent dyes was synthesized using a simple three-step procedure, and one of their reduced products, i.e. hydro-Si-oxazine HSiO3, has been utilized to sensitively detect hypochlorous acid and peroxynitrite generation by phagocytes in inflamed and pulmonary fibrosis diseased mice with emission wavelength beyond 750 nm.

Graphical abstract: Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm

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Supplementary files

Article information


Submitted
27 Apr 2020
Accepted
05 Jun 2020
First published
06 Jun 2020

Chem. Commun., 2020,56, 7718-7721
Article type
Communication

Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm

L. Wang, J. Liu, S. Zhao, H. Zhang, Y. Sun, A. Wei and W. Guo, Chem. Commun., 2020, 56, 7718
DOI: 10.1039/D0CC02322A

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