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Intense electrochemiluminescence from organic microcrystals accelerated H2O2-free luminol system for microRNA detection

Abstract

A kind of organic microcrystals,9,10-diphenylanthracene microcrystals (DPA MCs) was developed as a novel electrochemiluminescence (ECL) coreactant accelerator to efficiently catalyze dissolved O2 for more reactive oxygen species (ROSs) generation, achieving intense ECL for H2O2-free luminol system. Moreover, based on the ternary ECL system, a signal “off-on” ECL biosensor for microRNA-21 (miRNA-21) detection was constructed combining a sensitive target recycling amplification strategy and the enzyme-mediated recycling strand displacement reaction (RSDR).

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Supplementary files

Article information


Submitted
26 Mar 2020
Accepted
26 Jun 2020
First published
26 Jun 2020

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

Intense electrochemiluminescence from organic microcrystals accelerated H2O2-free luminol system for microRNA detection

Y. Zhuo, L. Wang, M. Jiang, Y. Chai and R. Yuan, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/D0CC02207A

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