Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Telomeric DNA–RNA-hybrid G-quadruplex exists in environmental conditions of HeLa cells

Author affiliations

Abstract

In the present study, we employed a 19F NMR approach to study the association of telomere RNA and DNA in vitro and in living human cells. We successfully characterized the DNA–RNA hybrid G-quadruplex (HQ) structure formed by telomeric DNA and RNA. We further demonstrated for the first time that an HQ conformation can exist in the environmental conditions of HeLa cells.

Graphical abstract: Telomeric DNA–RNA-hybrid G-quadruplex exists in environmental conditions of HeLa cells

Back to tab navigation

Supplementary files

Article information


Submitted
19 Mar 2020
Accepted
30 Apr 2020
First published
01 May 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Telomeric DNA–RNA-hybrid G-quadruplex exists in environmental conditions of HeLa cells

H. Bao and Y. Xu, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC02053B

Social activity

Search articles by author

Spotlight

Advertisements